本機配備有兩個雷射激發光源，分別為SHG laser at 473 nm and a He-Ne laser at 633 nm, 並配備有Y520, O580, R675 三種filter,其精確度可達每像素50um, 且不論Gel厚薄,其雷射強度均可穿透。可應用的螢光物質初步整理如下表:
FITC, Cy(TM) 2, SYBR(R) Green I & II, SYPRO(R) Orange, AttoPhos(TM), and others.
Cy5, DDAO phosphate and others
II. 放射線影像的補捉(Capturing Radioisotope Images)
隨機附有2片Image Plate(IP)，其上附著有5um結晶大小的BaFBr: Eu2+的粒子，這些粒子會補捉放射線能量，並隨後在雷射掃描時放出冷光(luminescence)，其解析度可達5 to 40 pixels/mm。使用後IP再以日光燈進行抹除(Erase)後重覆使用。以下列舉幾個特性以與X-ray autoradiography 方法做個比較。
Ultrahigh sensitivity. Several ten times more sensitive than film, and several thousand times depending on the sample.
Wider dynamic range. A wider range of 104 to 105 over the 102 range of the photographic method.
Superior linearity. The fluorescence emission is proportional to the dose in the entire range.
Higher spatial resolution. When compared with other electronic systems, a higher pixel density can be designed to meet the system purpose though less freely than film.
Digital electric signals are directly available from the reader. Computer processing or combination with other electronic systems is easy.
Due to an integral-type detector, the IP method produces less detection counting errors even at a high flux density, which often happen with pulse-type detectors such as the proportional counter tube and scintillation counter.
The accumulated background can be erased before use.